Educational orientation — not a diagnosis

Low mood and loss of interest

Persistent sadness, emptiness or loss of pleasure deserves attention, especially when daily functioning, sleep, appetite or hope are affected.

Important safety note

Immediate danger, suicidal intent, violence, severe confusion, sudden loss of function or loss of contact with reality require urgent local emergency or medical support.

Open crisis guidance →

Common signs

What people may notice

Loss of interest or pleasure
Low energy or slowed activity
Sleep or appetite change
Guilt, worthlessness or hopelessness
Withdrawal from work, family or friends

Several possibilities

This pattern may be associated with

Depression

Grief or adjustment difficulties

Burnout

Bipolar depressive episode, especially with a history of unusually elevated energy

Medical, hormonal or medication-related causes

This list is not exhaustive and does not establish a diagnosis.

When support may be useful

Look at persistence and impact

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Physical health and safety

What should not be overlooked

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Prepare for a useful consultation

Information worth noting

When it began and what was happening at the time.
Frequency, duration, triggers and what reduces or worsens it.
Sleep, appetite, energy, medicines, substances and medical conditions.
Effect on work, study, relationships and daily safety.

Clinical content principles

PRJI educational pages distinguish orientation from diagnosis, include physical-health cautions and direct urgent situations to local services. Content is informed by public mental-health information from WHO, NHS and NIMH and must be clinically reviewed before commercial launch.